hour with live coverage including interesting stories including the two inmates in florida who are now missing and also our dana bash sits down with senator ted cruz now that the government's back open, what does he have to say. right now we'll go to "sanjay gupta, m.d. "". good medicine or tmi, the genetic test some parents should do before they have kids. a new study concludes that oreos are actually addictive? really? plus, dick cheney opens up in his new book called "heart, an american medical odyssey." but, first -- obama care. you know, even the president has been frustrated by this. he says some of the problems on the sign-up website are just unacceptable. the federal government says techs are working around the clock to try to fix all this, and they say it's getting better but my friend elizabeth cohen who is on the story says it's not good enough.

>> reporter: i put in my user name and password and it didn't recognize it. error messages. page not found. system down. it's been a tough nearly three weeks for obama care. there were error messages or that little annoying kind of, like, twirly thing. >> i hate the twirly thing. >> reporter: hate it, hate it, right? i've been trying since day one to get an account and log in on healthcare.gov. i failed again. we couldn't make this page work. and again. it wouldn't log me in. and again. it's not working. when i've called the 1-800 number for help, the reps tell me volume is high and to try again during off-peak hours. so, i tried at 10:30 at night and 7:00 in the morning and still it didn't work. so finally, i set my alarm clock for 3:00 a.m. sunday morning. but guess what, the system was down for maintenance.

>> and here with me now is my friend and senior medical correspondent elizabeth cohen, it's amazing, everyone is talking about how challenging this has been. did you ever get through? >> i did eventually get through, so day 14 -- >> day 14. >> day 14 i managed to -- my login and pass word never worked that i tried to get originally, but i created a new account and i managed to get in. but it took me -- i had to try to create a new account many, many types before i succeeded at that. >> you were doing this to see how long it would take. i'm sure there people that gave up. >> right. i kind of had to game the game, i tried to create a new account, that didn't work. tried another new account, that didn't work. it was really persistence and sort of figuring things out. >> this is the federal site, right? >> right. >> we've been talking about the federal site which is healthcare.gov but 14 other states plus the district of columbia have their own sites and they seem to be working

better. the latest count more than 242,000 people have signed up for new insurance more than half in new york state alone. if people are watching and still having problems with this, what would you tell them? >> i would tell them if they're trying to log in and it's not working, they need to call the 800 number and specifically say, look, i've been trying and trying and trying, do identify need to reset my password, do i need to create a new account? ask those questions and i think that can really help. they said if i try at odd hours, so i tried at 10:00 at night and i tried at 3:00 in the morning. >> did you ever try calling that number ever? >> i did many times. >> was it hard to get through? >> easy to get through. a shout-out to the call reps. they're terrific. they're very helpful and they answer almost instantly. >> go figure. you would figure that would be the backlog the number of humans answering the phone. but they've got that part. >> it's the technology that seems to be the problem, not the people. >> there's a message here about technology, i'm not sure what it is. >> thanks. most people have a pretty strong opinion about dick

cheney, but whatever you think of him, you may be surprised to know over the past 35 years he's had five heart attacks, open heart surgery, a heart pump and even a heart transplant at age 71. all this is revealed in his new book called "heart" he's written with his cardiologist jonathan reiner. but he was so concerned about his health that two months after taking the oath as vice president, he took a very unprecedented action. >> basically what i did was i resigned the vice presidency effective march 28th of 2001. >> so nearly for your entire time as vice president there was a letter of resignation sitting there. >> pending. >> pending. >> he saw there was no provision in the constitution to replace a vice president who was alive but incapacita incapacitated, so he drew up a letter of resignation to give to the president. >> i richard b. cheney hereby resign the office of the vice president of the united states.

>> how did president bush react when you told him about that? >> he seemed a little surprised, but he thought it was a good idea. >> and you could see my full, exclusive interview with dick cheney sunday night on "60 minutes" and also right here next weekend on "sg md." coming up for any potential parents out there genetic testing before you get pregnant. what's out there, who needs to worry, and what can put your mind to rest. rest... while a body in motion tends to stay in motion. staying active can actually ease arthritis symptoms. but if you have arthritis, staying active can be difficult. prescription celebrex can help relieve arthritis pain so your body can stay in motion. because just one 200mg celebrex a day can provide 24 hour relief for many with arthritis pain and inflammation. plus, in clinical studies, celebrex is proven to improve daily physical function so moving is easier. celebrex can be taken with or without food. and it's not a narcotic. you and your doctor should balance the benefits

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for prospective parents out there the fear of passing on a genetic disease can lead to a painful dilemma, but there are tests you can undergo before you even conceive to learn if your baby's at risk and now some are pushing to make these standard practice. >> who wants pizza? >> me. >> the goulds appear to be a regular family. 5-year-old eden cannot walk or talk. shes a progressive neurological disorder, called ml-4. it's a rare disorder of eastern

or central european jewish descent. eden's development stopped at 18 months. doctors say she'll be blind by age 12 and she won't live beyond early adulthood. there is no treatment or cure. but ml-4 is preventible. so, how did this happen? the goulds knew that one in four are carriers for diseases like ml-4 or canavans or tay-sachs had is why they got screened before they were married or so they thought. >> my doctor screened me for two diseases and caroline's doctors screened her for those and two others and neither of us was screened for ml-4 and that's what we carried and gave it to our daughter. >> when both parents are carriers of a disease they have

a 25% of passing it on to their child, but the problem is there's no standardized screening, so they turned their fate into a mission. >> so, instead of asking why us, we decided to make sure that the tragedy of eden's story doesn't happen to another family. >> their work has grown into a new web-based education and screening program for 19 genetic diseases that are more common among a certain type of jews. established at emory university it is called j-screen and it allows visitors to request an at-home screening kit online and a genetic counselor delivers the results. last year eden became a big sister when the goulds added another daughter to their family. she is perfectly healthy. >> we believed in life again and that we had hope and we knew there would be joy and good times. i think she helped us see the world in a different way that we maybe had lost sight of once

eden was diagnosed. >> and eden will ultimately help many children she will never even meet. >> eden is really here to save people's lives. and she does that every day. and if that's what she's here to do, there is no more noble a life than that. i love you. oh, my goodness, what was that? >> now, for these parents it seems to make sense but is more testing something everyone should be doing? joining me to talk about that is genetic expert dr. michael gambela, thank you for joining us. most people think of genetic testing after the baby is born, they get the heel prick and they are testing for 30 different diseases. what we're talking about here is actually before they ever get pregnant, correct? >> correct. >> they should be getting tested for certain diseases at that point you're saying? >> i guess "should" is a word

i'm not sure i would use. but i think they should be offered the possibility to do carrier testing to know their risks if that's what they opt for. >> so, you are trying to figure out what their chances are of having a child who may have one of these diseases. how reliable are these tests? >> the tests are quite reliable. usually greater than 98% reliable. >> if somebody has the tests and they get the results back and it shows that they both carry a gene for this, what do you say to the parents? >> well, you inform them of what the risks are and what are some of the options they might have in order to have a healthy child. >> we talked about people of certain jewi isish descent in t piece, but other people that might be more likely to be suggested testing? >> well, i think every ethnic group has certain genetic diseases that are more prevalent in that group, so i think every group should consider being

informed about what they are at high risk for. >> some that are probably higher risk and i guess that would come out in a conversation with a genetic counselor. >> absolutely. if the couple comes back, they both carry the gene and they say i want to increase my chances of having a healthy baby, what can they do? >> there are a lot of options and they can certainly discuss that with maternal fetal medicine specialists. some of the options are they can use a sperm donor. they can use an egg donor. they could do in vitro fertilization with something called reimplantation diagnosis where we actually find out if the embryo is affected. they could adopt, so there are a lot of options open to people. >> all right, thank you, doctor, thank you for joining us. good information. appreciate it. from nature to nurture. addicted to oreos? you really could be. i'll explain, that's next. accid, just by talking to a helmet. it grabbed the patient's record before we even picked him up.

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♪ oh my best friend and an oreo cookie loves the crunchy chocolate i like the creamy middle ♪ ♪ been eating them since we were very little we'll always be friend with o-r-e-o ♪ >> do you remember that old oreo commercial? brings back some memories. well, believe it or not milk's favorite cookie turned 100 last year. but just this week researchers at connecticut college found the oreo is just as addictive as cocaine at least in lab rats. i want to point out that these

pictures of these lab rats with oreos are pretty darn cute but the researchers could have used any high-fat or high-sugar food and obviously a lot of people it caught their attention. we've got our go-to guy with food and eating addiction. i spent time in your lab going through your scanner myself. what did you think of the study? >> well, i thought it was -- provided very good evidence that the palatable foods, high-fat, high-sugar foods have a parallel that drugs of abuse do. >> that's amazing and i want to talk specifically about that. first of all, these were rats, what about in humans? you've done research in that particular area. >> yeah. no, and a lot of other people have actually administered food in the brain scanners and it's clear that palatable foods activate our reward centers the exactly the same way as drugs of abuse and there's a parallel set of findings coming out of the

rat literature that looks exactly like what we see with humans as well. >> when people think of drug and abuse cocaine was the example they gave in the study and people said that's really addictive. cocaine is very addictive and now we're drawing this comparison between that and sugar, high-fat, high-sugar foods. let me start by asking this, how do you define addiction? what does that mean from your perspective? >> addiction really is composed of two concepts. one is the idea of abuse, that you have problems from use. people who use cocaine lose their jobs or become, you know, rejected from their family because of the problems. those are negative consequences from use. parallels with overeating would be that you develop medical problems from overheeating. but there's also dependence when you get your body physiologically used to having cocaine or palatable food on board, it creates a sense of tolerance so you have to escalate the amount of cocaine

to get the same effect and there's evidence the same thing happens, the more you eat oreos, the more you'll escalate your intake of oreos to experience the same degree of pleasure. >> so you start craving them more -- if you eat some, you start craving more and therefore eating more than ever. it sounds very cyclical. >> yeah, there's two changes that happen in our brains as, you know, we eat a whole bunch of palatable foods, we get a blunted response of our reward circuitry which is akin to drug abuse and escalating the amount of cocaine you have to do to get high, you would similarly have to escalate the amount of oreos you eat to get the same amount of pleasure, the next aspect is a little bit more assiduous, you get attuned to the cues to food or drugs and when you see the cues you start craving the food or the drugs and that's what really maintains the behavior. >> the idea of equating in some ways sugar or cocaine, the brain only has one sort of pleasure center or pleasure area.

does it discriminate between different types of pleasure? can we really put these on the same sort of ground, sugar and cocaine? >> so, they're not exactly the same thing and slightly different areas of the reward circuitry's involved in each. but, you know, this does really extend some work by a surgeon out of france very nicely that found that rats would liver press for sweet taste just as much as they liver press for cocaine and the whole field was very incredulous about it when he initially published the findings but the new data line right up with that. >> i saw the study where the rats would be pushing on the liver just as vigorously for the sugar as the cocaine. let me ask you something else. people have heard the numbers regarding the obesity epidemic, 35% of americans are not just overweight but obese. when we release these kind of studies, is it saying addiction is in some way an excuse? are the people who are obese, is this -- is this more because of this addiction? how much of this is willpower versus what's happening in the brain? >> well, there's two components

of that. certainly our ability to operate executive control and make choices of purr sufing goals like employment and the long-term relationship over drugs of abuse or overeating is very essential. but very new research is finding that there's individual differences in how quickly we learn to associate cues with reward from food or drugs and the people who rapidly learn these cues for reward, they're the ones that get sucked into the habit much more than other people. so, there are genetic differences that have an influence on this. so, willpower, putting it very concisely, some people don't have to bring much willpower to the table wheresas other people have to bring a great deal. >> thank you, shed some interesting insights to that, appreciate that. a check of your top stories minutes away. but still ahead, doogie howard m.d. versus sanjay gupta,

m.d.? >> he wrote a poem and proposed to her in the last line. >> doogie. >> i'm losing all of them! >> and more than a few laughs with andy cohen and soleil moon frye. that's next. i couldn't wait to see her again. but i didn't want her to see my psoriasis. no matter how many ways i try to cover up, my psoriasis keeps showing up. all her focus is on me. but with these dry, cracked, red, flaky patches,

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we want to take a moment now and congratulate a few of our fit nation alumni. you may remember nancy clinger who was in last year's bunch, when we first met her, she was reeling from a recent divorce.

she recently completed a half ironman race in augusta, georgia. unbelievable. three of our other alumni, they did a relay in that race. i remember two of them did their first triathlon just a few weeks ago in malibu. the key here is that all of them started small, one step at a time, and they transformed themselves from couch potatoes into triathletes, and you can do this as well. i'm excited to announce we're now accepting submissions for our 2014 fit nation challenge team and logon to cnn.com/fitnation and learn much more and join us. let's stay on topic here, you know, one of the things i've really come to love about the triathlons is the sport of cycling. this is a lot of fun, and for a lot of people it can be intimdating when you start but it doesn't have to be. for somebody who may be, you know, in their late 40s, late 50s, who wants to get back into cycling again, doctor, what

would be the thing that you sort of tell them to be mindful of? >> i think the first thing is be mindful of your current injuries. make sure those are addressed and make sure you have some basic core stability, good range of motion, and then go to a proper bike shop. get fitted for a bike. >> you know, there's cars passing by us as we're talking. the interaction of bikes and traffic, first of all, we're going with traffic which is how you should ride, right? >> yes. >> what else? >> bikers need to be alert. we're totally unprotected. running red lights is not a good idea. stop at a stop sign. stop at red lights. as you're riding, you want to be watching the cars. you want to try to get a feeling, are they going to turn, are they indicating, watch for doors opening. it's a great sport. you see some beautiful things you'd never notice in your car and you get some exercise while you're doing it. >> you notice the hills more. >> everything. you definitely notice the hills more. >> do you stretch after every

ride? >> i do like to stretch after i ride. tilt your pelvis and you can feel a stretch. put your leg up and do a hamstring stretch. do the other side. >> got it. >> you are spending just a few minutes afterwards. >> a few minutes afterwards. stretch your gluts out and stretch your back. >> it's nice for the back. i definitely feel that, awesome. and you do feel the hills for a long times afterwards, but it's really good exercise. before we go i got to have late night fun with bravo's andy cohen and also soleil moon frye. >> guess what sanjay gupta got into medical school when he was still a kid, just 16. wow. in honor of that we're going to play doogie or gupta, i'll give you a fact and you tell me if it's doogie